Ferritin
Test Overview
The Ferritin test measures the level of ferritin, a protein that stores iron in the body. Ferritin levels reflect the body’s iron reserves and help in diagnosing iron deficiency or iron overload conditions.
Test Uses
- Diagnose iron deficiency anemia.
- Evaluate iron overload disorders, such as hemochromatosis.
- Monitor iron levels in chronic diseases, including kidney disease, liver disease, or inflammatory conditions.
- Assess iron status in individuals with unexplained fatigue, hair loss, or restless leg syndrome.
Ferritin Test Results & Ranges
| Test Component: | Normal Range: | Abnormal (Possible Conditions): |
|---|---|---|
| Ferritin (ng/mL) | Men: 24–336 ng/mL | Low (<24 ng/mL) → Possible iron deficiency, anemia, chronic blood loss. High (>336 ng/mL) → Possible iron overload (hemochromatosis), liver disease, chronic inflammation, or infection. |
| Women: 11–307 ng/mL | Low (<11 ng/mL) → Possible iron deficiency, pregnancy-related anemia. High (>307 ng/mL) → Possible iron overload, chronic disease, or inflammation. | |
| Children: 7–140 ng/mL | Low (<7 ng/mL): Possible iron deficiency. High (>140 ng/mL): Possible iron overload or chronic inflammation. | |
- Low ferritin levels are a strong indicator of iron deficiency anemia.
- High ferritin may indicate iron overload, inflammation, or chronic disease (e.g., liver disease, infections, autoimmune disorders).
Expected Turnaround Time
- Results Available: Typically within 24 – 48 hours.
Specimen Requirements
- Sample Type: Blood sample (venipuncture).
- Container: Serum separator tube (SST, gold or red-top tube).
Collection Instructions
- Fasting: Not required, but some doctors recommend morning fasting for more accurate results.
- Avoid iron supplements for at least 24 hours before the test.
Test Details
Clinical Use: Ferritin is the main storage form of iron, and low levels indicate depletion of iron stores. Iron deficiency is common in menstruating women, vegetarians, and individuals with chronic blood loss (e.g., gastrointestinal bleeding, ulcers). High ferritin levels may be caused by chronic inflammation, infections, or conditions like hemochromatosis (excess iron storage disease).
Limitations: Ferritin is an acute-phase reactant, meaning it can be elevated due to inflammation, infection, or liver disease even if iron stores are normal. A complete iron panel (serum iron, TIBC, transferrin saturation) is often needed to fully assess iron status.
The Ferritin test is a key marker for iron storage levels, helping diagnose iron deficiency anemia or iron overload conditions like hemochromatosis.